While biological and lifestyle determinants of reproductive health are well documented globally, comprehensive data integrating socio-demographic, lifestyle, and health correlates within a contemporary Polish context remain limited. This study aimed …
β-Glucuronidase (β-G, EC 3.2.1.31) reverses phase II glucuronidation, and microbial β-G at the gut-liver interface reactivates biliary and circulating conjugates, closing enterohepatic loops for drugs, estrogens, bile acids, and bilirubin. …
Does the endometrium of oligo-ovulatory women with polyendocrine metabolic ovarian syndrome (PMOS) exhibit menstrual cycle phase-specific transcriptomic alterations compared to women without PMOS?
Female reproductive health is increasingly affected by conditions such as infertility, polycystic ovary syndrome (PCOS), and endometriosis. Given the impact of modifiable lifestyle factors, nutrition has emerged as a potential …
To investigate, using transvaginal ultrasound imaging, the overlap between polycystic ovarian morphology (PCOM) and endometriosis, and to explore demographic and clinical factors associated with their coexistence across endometriosis phenotypes.
Orofacial pain (OFP) is a multidimensional clinical problem that includes conditions such as temporomandibular disorders (TMD). It is often associated with chronic overlapping pain conditions (COPCs), including gastrointestinal, gynecological and …
The widespread use of plastic has led to exposure to chemicals like bisphenols (BPs), particularly bisphenol A (BPA), which are crucial in the production of polycarbonate plastics and epoxy resins. …
Polyunsaturated fatty acids (PUFAs) are hypothesized to modulate female reproductive endocrine disorders, yet their causal relationships remain elusive. We employed Mendelian randomization (MR) to investigate bidirectional causality between circulating PUFAs …
The human microbiome, a dynamic endocrine organ, exerts profound systemic influence through the production of bioactive metabolites. While the microbiome-gut-brain axis is well-established, the direct conduit between the gut microbiota …
Cardiovascular disease (CVD) remains the leading cause of mortality in women, yet sex-specific risk factors are usually not included in conventional predictive models. Specifically, heart failure (HF) in women may …