Endometriosis affects approximately 10% of women of reproductive age and is associated with increased risks of infertility and miscarriage. Although the spontaneous miscarriage rate in women with endometriosis is higher …
Assisted reproductive technologies (ART) are widely used to address infertility; however, they are costly, associated with medical risks, and often yield suboptimal clinical outcomes. Natural Procreative Technology, also known as …
The endometrium is a highly dynamic tissue central to female reproductive function, undergoing nearly 500 cycles of proliferation, differentiation, shedding, and regeneration throughout a woman's reproductive life. This remarkable regenerative …
Many experimental and clinical studies published so far demonstrate that melatonin-produced mainly by the pineal gland located deep in the middle of the brain, between the two cerebral hemispheres, and …
Global fertility rates continue to decline despite advancements in assisted reproductive technologies, highlighting a significant gap in our understanding of the mechanisms underlying preconception physiology. In this commentary, we review …
Decidualization is the transformation of endometrial stromal cells into functionally specialized cells during the early stages of pregnancy. Occurring in mammals that develop invasive hemochorial placentae, decidualization is a pivotal …
Endometriosis, chronic endometritis (CE), unexplained infertility (UI), and recurrent pregnancy loss (RPL) are gynecological conditions frequently associated with inflammation and alterations in the endometrial microbiome. The presence of bacterial vaginosis-associated …
MiRNAs regulate gene expression, impacting reproductive health, such as infertility and implantation failure. This study investigated the association between miRNA polymorphisms and male infertility (azoospermia, oligospermia), female infertility (endometriosis), and …
The uterus is a complex organ that requires precise signaling networks to mediate functions necessary for homeostasis and reproductive processes. The transforming growth factor β (TGFβ) superfamily regulates integral signaling …
Endometriosis (EMs) is a chronic inflammatory disease characterized by the presence of endometrial tissue in the non-uterine cavity, resulting in dysmenorrhea, pelvic pain, and infertility. Epidemiologic data have suggested the …