Endocrine disrupting chemicals (EDCs) have been associated with disorders affecting female reproductive health, although the precise causal connections and underlying pathways between these substances and such disorders remain incompletely elucidated. …
Pharmacogenetics is an emerging discipline that explores how genetic variants affect drug response, potentially leading to side effects or treatment failure. Although widely applied in other medical specialties, its use …
Iron is an essential micronutrient element for human. It participates in energy metabolism, enzyme activation, immune system and other metabolic functions. In this review, the potential role of iron in …
tRNA-derived small RNAs (tsRNAs) are a class of non-coding RNAs(ncRNAs) generated from precursor or mature tRNAs under stress conditions, such as starvation, hypoxia, or oxidative stress. They are broadly classified …
A healthy reproductive system is fundamental to human fertility. N6-adenosine methylation (m6A), the most prevalent RNA modification in eukaryotes, plays a critical role in regulating RNA metabolism, including splicing, degradation, …
Reproductive disorders affect millions of women worldwide, playing a crucial role in determining female fertility health and quality of life. Conventional methods such as surgery, hormone therapy, and assisted reproductive …
Non-human primates (NHPs) are considered important models for the study of reproductive diseases, due to their anatomical and physiological similarities to humans. However, studies on spontaneous lesions of the reproductive …
Di(2-ethylhexyl) phthalate (DEHP), the most prevalent plasticizer worldwide, can enter the human body via various exposure pathways, including ingestion, inhalation, skin contact, and medical applications. It has been observed to …
The DNA repair enzyme 8-oxoguanine DNA glycosylase-1 (OGG1) plays a crucial role in the initiation of DNA base excision repair pathway by recognizing and excising the oxidative base lesions including …
Current treatments for endometriosis are unsuitable for women who wish to conceive. To verify the supposed beneficial effects of Graptophyllum pictum (G. pictum) on reproductive diseases and inflammation, endometriosis was …