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Decidualization potential of endometrial mesenchymal stem cells and their role in reproductive health.

The establishment of a successful pregnancy depends on proper embryo development and coordinated endometrial differentiation, particularly through the process of decidualization. Mesenchymal stem/stromal cells (MSCs), especially those derived from endometrial …

Published: May 23, 2026, midnight
Stromal-only endometriosis catamenial pneumothorax: A diagnostic algorithm with potential pitfalls.

Catamenial pneumothorax (CP) is a rare form of recurrent spontaneous pneumothorax occurring synchronously with menstruation and represents the most common manifestation of thoracic endometriosis. CP predominantly involves the right hemithorax …

Published: May 19, 2026, midnight
Hypoxia-mediated epigenetic silencing of YTHDF2 promotes endometriosis progression via the NFE2L1-NF-κB axis.

Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic growth of endometrial-like tissues. N6-methyladenosine (m6A) modification regulates diverse cellular processes, yet its role in EMs remains unclear. Here, we …

Published: May 19, 2026, midnight
Single-cell profiling and machine learning identify cuproptosis-related fibroblast subpopulations and fibrogenesis modulator AEBP1 in endometriosis.

Endometriosis is characterized by progressive fibrosis and limited therapeutic options. Cuproptosis, a copper-dependent form of regulated cell death, has been implicated in multiple pathological conditions, but its relevance to fibroblast-mediated …

Published: May 18, 2026, midnight
HSD11B1 suppresses ferroptosis in endometrial stromal cells through the JUND/IL-10 axis to promote endometriosis progression.

Endometriosis (EMs) is a common gynecological disorder characterized by ectopic endometrial tissue growth, leading to chronic inflammation and pelvic pain. Despite its high prevalence, the molecular mechanisms underlying EMs remain …

Published: May 18, 2026, midnight
Nuclear factor IX promotes endometriosis progression through transcriptional activation of tetraspanin-2.

Endometriosis is a benign yet aggressive disease characterized by enhanced proliferation and invasion of ectopic endometrial tissue. Identifying upstream regulators that co-regulate these processes will provide novel insights into endometriosis …

Published: May 16, 2026, midnight
Glycolytic reprogramming and MYH10 K1520 lactylation mediate eutopic endometrial collagen I deposition driven by PKM2-packaged ectopic endometrial extracellular vesicles.

Endometriosis (EMs) is characterized by ectopic lesions that disrupt endometrial decidualization, a process frequently accompanied by aberrant collagen deposition and closely linked to clinical infertility. Extracellular vesicles (EVs) are key …

Published: May 11, 2026, midnight
The main active monomer of Dan'e-fukang soft extract, liquiritin, inhibits the inflammation and invasion of ectopic endometrial stromal cells through down-regulation of CCL2.

The study explored the mechanism of Dan'e-fukang soft extract in treating endometriosis (EMs) through network pharmacology. The main active ingredients of Dan'e-fukang soft extract were analyzed based on the traditional …

Published: May 7, 2026, midnight
Phenotypic and Functional Characterisation of Primary Endometriotic Stromal Cells for In Vitro Model Development - EMJ

Phenotypic and Functional Characterisation of Primary Endometriotic Stromal Cells for In Vitro Model Development EMJ

Published: April 30, 2026, 6:44 a.m.
miR-769-5p inhibits cellular behaviors associated with endometriosis progression by directly targeting follistatin in vitro.

The pathogenesis of endometriosis (EM) remains intricate and multifactorial. This study aimed to investigate the biological functions of microRNA-769-5p (miR-769-5p) in an in vitro model of EM. Serum was obtained …

Published: April 30, 2026, midnight
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