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Is colorectal resection necessary to improve pain and fertility outcomes in patients with deep endometriosis?

Bowel endometriosis is often considered an indication for extensive surgical management, including colorectal resection, in women undergoing surgery for concomitant endometriosis at other sites. However, several contemporary studies show little …

Published: April 8, 2026, midnight
Characterization of endometriosis in patients with Mullerian anomalies using the Enzian classification: A retrospective cohort study.

Mullerian anomalies are frequently associated with endometriosis, particularly in the presence of genital tract obstruction; however, the anatomical distribution and determinants of disease in this population remain incompletely characterized. Most …

Published: April 7, 2026, midnight
Major postoperative complications after endometriosis surgery: incidence and outcomes from a multicenter French cohort.

Surgery is a therapeutic option for patients with deep endometriosis presenting with infertility and/or pain refractory to medical treatment. Major postoperative complications may impair quality of life and delay the …

Published: April 3, 2026, midnight
Differences in epigenetic age acceleration according to a diagnosis of endometriosis/adenomyosis: the Norwegian Mother, Father and Child Cohort Study.

Women with endometriosis and adenomyosis have an increased risk of age-dependent diseases such as cardiovascular disease and cancer. Whether this reflects differences in biological age is unknown.

Published: March 30, 2026, midnight
Revealing the immune landscape of menstrual blood: unlocking insights into activation, exhaustion, and mitochondrial mass for reproductive health.

Reproductive disorders such as endometriosis and polycystic ovary syndrome (PCOS) are increasingly recognized as immune-mediated conditions, yet their immunopathology remains poorly understood. Menstrual blood, a noninvasive and biologically relevant sample, …

Published: March 27, 2026, midnight
Safety and Reproductive Outcomes of Minimally Invasive Nerve-Sparing Surgery for Deep Endometriosis in Infertile Women: A One-Year Follow-Up Study.

Background/Objectives: Deep endometriosis is a chronic inflammatory disease that significantly affects fertility. The objective was to evaluate the magnitude of the effect of minimally invasive nerve-sparing complete excision of endometriosis …

Published: March 17, 2026, midnight
Bidirectional prospective relationship of endometriosis with major depressive disorder: the mediating role of metabolic biomarkers.

Endometriosis and major depressive disorder (MDD) pose significant global health burdens. Despite pathophysiological overlaps, existing epidemiological studies predominantly examine their unidirectional associations, often constrained by cross-sectional designs and small sample …

Published: March 16, 2026, midnight
Comment on "Dienogest treatment in women with endometriosis: A retrospective cohort study in Taiwan".

Published: March 13, 2026, midnight
The #Enzian Classification as a Predictor of Hormonal Therapy Response in Endometriosis-Associated Pain: A Retrospective Cohort Study in a Referral Center.

To evaluate whether ultrasound-based #Enzian classification predicts pain profiles and response to hormonal therapy in patients with endometriosis. Endometriosis is a chronic inflammatory disease affecting 10% of reproductive-age women, often …

Published: March 11, 2026, midnight
Exosome-Enriched Hub Gene Networks Identify Diagnostic Biomarkers and Repurposable Therapeutic Targets in Endometriosis.

Endometriosis is a heterogeneous chronic inflammatory disorder associated with substantial diagnostic delay and limited therapeutic options, highlighting the need of robust non-invasive biomarkers and actionable molecular targets to complement existing …

Published: March 11, 2026, midnight
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