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Orchestrating the gut microbiota-mitochondrial-immune axis in gynecological diseases: mechanisms and dual-targeting therapeutic strategies.

The "gut microbiota-mitochondria axis" has become the core hub connecting the metabolism, immunity, and endocrine regulation of gynecological diseases. In this review, the hierarchical regulation mechanism of this axis is …

Published: July 1, 2026, midnight
MRI-based morphology of ovarian clear cell carcinomas.

Ovarian clear cell carcinoma (CCC) is a distinct histological subtype of epithelial ovarian cancer characterized by unique biological behavior and heterogeneous clinicopathological features. In contrast with other epithelial ovarian malignancies, …

Published: June 26, 2026, midnight
The effects of plasma protein levels on the risk of endometriosis: A Mendelian randomization study.

Endometriosis is a prevalent gynecologic disorder that significantly impacts women's health. However, its underlying pathogenesis remains unknown. This study aimed to ascertain causal associations between plasma protein levels and endometriosis …

Published: June 10, 2026, midnight
Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry.

Anxiety is heritable and exists on a continuum, with symptoms ranging from adaptive threat response to clinical disorder. Here we performed a genome-wide association meta-analysis of generalized anxiety symptom severity …

Published: June 9, 2026, midnight
Gut microbiota dysbiosis in endometriosis: mechanistic insights and gut microbiota-targeted therapeutic strategies.

Endometriosis (EMs) is a prevalent, estrogen-dependent gynecological disorder characterized by the ectopic implantation and proliferation of endometrial-like tissue outside the uterine cavity, affecting approximately 10% of reproductive-aged women globally. Despite …

Published: June 5, 2026, midnight
A woman's worth: Self-compassion as a mediator between optimism and beliefs about motherhood, identity, and infertility of women with endometriosis.

The aim of the present study was to analyze the mediating role of self-compassion between trait optimism and beliefs about woman identity, motherhood and infertility among women with endometriosis, adjusting …

Published: June 4, 2026, midnight
Correlations Between Ultrasound Features and Histological Findings in Adenomyosis: A Single-Center Retrospective Study.

Adenomyosis is a benign gynecologic condition characterized by ectopic endometrial glands and stroma present within the myometrium. Background/Objectives: The gold standard in diagnosis is the histology of hysterectomy specimens. Due …

Published: May 22, 2026, midnight
Developmental Versus Chromosomal Competence in Endometriosis: A Stepwise IVF Outcome Analysis.

Background and Objectives: Endometriosis is a multifactorial gynecological condition associated with impaired fertility; however, its impact on embryo competence remains incompletely understood. This study aimed to evaluate embryo competence through …

Published: May 21, 2026, midnight
Exploring the Genetic Influence of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) on Inflammatory Biomarkers in Endometriosis Progression.

Investigating the genetic influence of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) on key inflammatory biomarkers-Interleukin-1β, Interleukin-6, and high-sensitivity C-reactive protein (hsCRP) and to evaluate their association with disease progression …

Published: May 7, 2026, midnight
Mid-Cycle Pain in Endometriosis: Clinical Correlations and Potential Etiological Factors.

To characterize differences between individuals with and without mid-cycle pain in a registry cohort with endometriosis.

Published: April 23, 2026, midnight
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