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Evidence-based recommendations for advancing the chronic pelvic pain syndrome management by the paradigm change from reactive symptom suppression to proactive 3PM-guided patient-centered care.

Chronic pelvic pain syndrome (CPPS) encompasses a heterogeneous group of debilitating conditions including interstitial cystitis/bladder pain syndrome (IC/BPS), chronic abacterial prostatitis, endometriosis, and pelvic congestion syndrome, among others. Despite advances …

Published: Aug. 28, 2026, midnight
Are gastrointestinal, gynecological and urogenital chronic overlapping pain conditions (COPCs) predisposing or perpetuating factors for orofacial pain (OFP)? A systematic review.

Orofacial pain (OFP) is a multidimensional clinical problem that includes conditions such as temporomandibular disorders (TMD). It is often associated with chronic overlapping pain conditions (COPCs), including gastrointestinal, gynecological and …

Published: July 25, 2026, midnight
Microbiome and chronic pelvic pain in women: a mini-review.

Chronic pelvic pain (CPP) is a prevalent, disabling syndrome encompassing overlapping disorders such as endometriosis/adenomyosis, bladder pain syndrome/interstitial cystitis, irritable bowel syndrome, vulvodynia, and myofascial pain syndrome. Despite distinct clinical …

Published: July 24, 2026, midnight
Systematic Laparoscopic Excision and Reconstruction of Bladder Endometriosis With Deep Myometrial Infiltration: A Step-by-Step Surgical Technique and Educational Case Report.

Bladder deep endometriosis is an uncommon but clinically significant phenotype of deep infiltrating endometriosis (DIE), and the coexistence of full-thickness detrusor disease with deep myometrial infiltration of the anterior uterine …

Published: July 14, 2026, midnight
Are We Missing the Bladder? Reflections on Endometriosis and IC/BPS.

Endometriosis and interstitial cystitis/bladder pain syndrome (IC/BPS) frequently coexist in women with chronic pelvic pain, yet overlapping symptoms and non-standardized diagnostic pathways often delay recognition of dual pathology. We propose …

Published: July 8, 2026, midnight
A prospective surgical evaluation of the coexistence of endometriosis and interstitial cystitis/bladder pain syndrome.

Endometriosis and interstitial cystitis/bladder pain syndrome (IC/BPS) frequently coexist; however, diagnostic delays and non-standardized criteria limit accurate identification of these conditions.

Published: July 8, 2026, midnight
Multimorbidity in Chronic Overlapping Pain Conditions: From Burden to Integrated Care.

Chronic overlapping pain conditions (COPCs) refer to a set of chronic pain disorders that frequently co-occur and may involve partially overlapping mechanisms. The U.S. National Institutes of Health currently recognizes …

Published: June 22, 2026, midnight
Gynecologic Manifestations of Interstitial Cystitis/Bladder Pain Syndrome.

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common source of chronic pelvic pain. The aim of this study was to determine the gynecologic comorbidities associated with bladder pain in the …

Published: June 18, 2026, midnight
Preclinical models of female pelvic pain disorders.

Pain is influenced by a complex interplay of biological, psychological, and social factors. Sex has emerged as a key determinant of vulnerability to chronic pain and a major risk factor …

Published: May 20, 2026, midnight
A meta-umbrella review of risk factors for vulvodynia: evidence from demographic, psychosocial, and biomedical domains.

Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associated risk factors are lacking …

Published: March 25, 2026, midnight
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