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Natural Products Targeting Oxidative Stress-Inflammation Crosstalk in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder marked by ectopic endometrial-like tissue growth, resulting in pelvic pain, infertility, and significant declines in quality of life. Despite extensive research, current therapies …

Published: July 25, 2026, midnight
Generation and Characterization of a Rdh1-iCre Line to Study Uterine Glandular Biology.

The uterus is an essential organ for fetal development in most mammals. Uterine glands, highly conserved structures in the mammalian uterus, play critical roles in the establishment and maintenance of …

Published: July 25, 2026, midnight
Systems-level genomic analyses reveal shared mechanisms underlying endometriosis and sleep disorders.

We examined clinical, genetic, and molecular links between sleep disorders and endometriosis. Women aged 20-54 years in NHANES 2005-2006 were analyzed with survey-weighted logistic regression. Bidirectional two-sample Mendelian randomization (MR) …

Published: July 25, 2026, midnight
FOSL2-driven SASP in endometrial stroma promotes the inflammation of endometriosis.

Endometriosis (EMs) is characterized by chronic pelvic inflammation, but the etiology of this inflammation remains poorly understood. The senescence-associated secretory phenotype (SASP), whereby senescent cells secrete pro-inflammatory cytokines, is a …

Published: July 24, 2026, midnight
Longitudinal trends in general, central, and visceral adiposity indices among women with endometriosis: a population-based study.

Previous studies have suggested the close link between endometriosis and body size index. However, there are inconsistent associations between central, general, and visceral adiposity index and endometriosis. This study aimed …

Published: July 23, 2026, midnight
Relationship and mental health outcomes after childbirth among women with endometriosis: An 8-year follow-up study.

BackgroundTransitioning to parenthood is stressful for relationships. Women with endometriosis face several health challenges, which may further strain their relationships when they become parents. However, it remains uncertain whether this …

Published: July 22, 2026, midnight
Effect of pain management, supervised exercise, and pelvic floor muscle training on sexual function in women with endometriosis: A randomized controlled trial.

Pelvic and genital pain is a common symptom among women with endometriosis and may negatively affect sexual functioning. Pelvic floor muscle training (PFMT) may improve sexual functioning, but whether this …

Published: July 22, 2026, midnight
A rare case of life-threatening haematochezia in pregnancy associated with decidualized rectal mucosal endometriosis.

To report and emphasize the difficulty in diagnosis and management of acute gastrointestinal bleeding due to recurrent endometriosis in pregnancy.

Published: July 22, 2026, midnight
p53-mediated epigenetic regulation in the pathogenesis of endometriosis.

Endometriosis (EMs) is a common gynecological disorder affecting reproductive‑aged women, characterized by ectopic endometrial growth and chronic pelvic pain that severely impairs quality of life. Although its pathogenesis remains incompletely …

Published: July 21, 2026, midnight
Integrative Transcriptomic Analysis Identifies a Key Candidate Gene Bridging Inflammation and DNA Repair in Endometriosis.

Endometriosis is a chronic, estrogen-dependent inflammatory disorder characterized by the ectopic implantation of endometrial-like tissue. Although retrograde menstruation is highly prevalent, only a subset of women develops the disease. This …

Published: July 21, 2026, midnight
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