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From polygenic risk to functional genomics: a framework for precision gynecological disease modeling.

Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a framework integrating …

Published: Aug. 27, 2026, midnight
Body image concerns, disordered eating, and negative affect in women with and without gynecological conditions.

BackgroundResearch has suggested that some gynecological conditions are associated with body image, disordered eating behaviors, and mental health concerns. This has been studied in polycystic ovarian syndrome and endometriosis populations, …

Published: Aug. 17, 2026, midnight
Reframing endometriosis care in low-resource settings: a pragmatic 5R framework for recognition, rule-out, relief, referral and review.

Endometriosis is a chronic inflammatory gynecological condition associated with severe dysmenorrhea, chronic pelvic pain, deep dyspareunia, cyclic bowel or urinary symptoms and infertility. It is also linked to psychological morbidity, …

Published: Aug. 17, 2026, midnight
Synchronous right colon adenocarcinoma and sigmoid endometriosis mimicking a second primary carcinoma: a case report.

Intestinal endometriosis is a benign gynecological condition that frequently involves the rectosigmoid colon. Its synchronous occurrence with colorectal cancer is exceptionally rare and diagnostically challenging, particularly when mimicking a second …

Published: Aug. 13, 2026, midnight
"Why Aren't You Listening?": How Experiences of Endometriosis, Medical Dismissal, and Psychological Distress Should Influence Assessment and Interventions.

Background/Objectives: Endometriosis is a chronic gynecological condition affecting approximately 10% of women of reproductive age and is associated with chronic pain, fatigue, infertility, and reduced quality of life. Beyond its …

Published: Aug. 11, 2026, midnight
Gut commensal Olsenella profusa promotes endometriosis via lysophosphatidylcholine metabolite.

Endometriosis (EM) is an intractable gynecological condition with uncertain etiology. Gut microbiota have been increasingly implicated in EM, yet the underlying mechanisms remain unclear. Here, we identify a gut microbe-metabolite-uterus …

Published: Aug. 5, 2026, midnight
Activin A is a functional component of the anti-endometriotic drug Endoferin.

Endometriosis is a prevalent gynecological condition affecting up to 25-40% of women with infertility. Endoferin, a protein complex derived from the bovine ovarian follicles, has demonstrated high efficacy in clinical …

Published: July 31, 2026, midnight
The role of tumor necrosis factor alpha in regulating CYFRA 21-1 as a potential biomarker for endometriosis: A cross-sectional study.

Background: Endometriosis is one of the most common gynecological conditions, and the gold standard for its diagnosis is laparoscopy. Cytokeratin fragment 21-1 (CYFRA 21-1) has emerged as a potential biomarker …

Published: July 14, 2026, midnight
Attachment, emotion regulation and quality of life in women with a diagnosis of endometriosis: a cross-sectional study.

Endometriosis, a prevalent gynecological condition, significantly impacts physical, psychological, and social well-being. This study explores the relationship between attachment styles, emotion regulation difficulties, and quality of life in women with …

Published: July 9, 2026, midnight
Differential expression of microRNAs after induction of endometriosis in baboons.

Endometriosis is an inflammatory chronic gynecological condition that affects 10-15% of reproductive-age women which causes pelvic pain and infertility. The disease is characterized by the growth of endometrial tissue outside …

Published: July 8, 2026, midnight
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