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H2S-Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety.

Despite ongoing challenges in developing effective non-surgical and non-hormonal treatments for endometriosis, the psychological manifestations of the disease-particularly anxiety-remain comparatively underexplored. In this study, a hydrogen sulfide (H2S)-releasing aspirin derivative, …

Published: Feb. 8, 2026, midnight
Targeting HSP90 as a therapeutic approach for endometriosis: insights from proteomic analysis.

Endometriosis, a chronic inflammatory condition characterized by pain and infertility, remains a clinical challenge. Current hormonal and surgical treatments are often limited by side effects and high recurrence rates. In …

Published: Feb. 7, 2026, midnight
The role of Fusobacterium nucleatum in the pathogenesis of endometriosis: A microbial and microenvironmental perspective.

Endometriosis is a chronic, inflammatory gynecological condition characterized by the ectopic growth of endometrial-like tissue, with an unclear etiology and limited treatment efficacy. Recent studies implicate the oral and gut …

Published: Feb. 4, 2026, midnight
Effect of Astragalus sinicus Ethanol Extract on Menopausal Symptoms in an Ovariectomized (OVX) Mouse Model.

As the aging population grows, the proportion of postmenopausal women is also increasing. Menopause can cause various symptoms and reduce quality of life. Hormone replacement therapy (HRT) is a common …

Published: Jan. 23, 2026, midnight
Therapeutic potential of epigallocatechin gallate in gynecologic cancer, endometriosis, polycystic ovary syndrome: a mechanistic and translational perspective.

Tea, among the most widely consumed beverages worldwide, is rich in polyphenolic compounds known as catechins, particularly epigallocatechin gallate (EGCG). This review aims to synthesize recent findings and ongoing controversies …

Published: Jan. 13, 2026, midnight
Histologic Comparison of Ablative Techniques for Endometriosis: a Randomized Trial.

To compare ablative energy technologies and evaluate their ability to destroy in vivo endometriosis tissue in humans.

Published: Jan. 10, 2026, midnight
Development of a three-dimensional culture model of endometrium to study embryo-uterine interactions.

Three-dimensional (3D) culture systems provide physiologically relevant models that better replicate in vivo cell architecture and function compared to the conventional two-dimensional cultures. In reproductive biology, 3D models of endometrial …

Published: Jan. 6, 2026, midnight
SLC25A1-Mediated Cholesterol Accumulation Promotes Endometriosis Progression by Enhancing Endometrial Stromal Cell Proliferation, Invasion, and M2 Macrophage Polarization.

Endometriosis is an estrogen-dependent chronic inflammatory disorder. Cholesterol (CHO) has been reported to be closely associated with estrogen synthesis and inflammatory responses. Nevertheless, the mechanisms underlying the effects of cholesterol …

Published: Jan. 1, 2026, midnight
Human Endometriosis Scaffold Can Enhance Cell Seeding and Engraftment; an In Vitro and In Vivo Study.

The extracellular matrix (ECM) critically influences cell behavior, yet its properties in human endometrial lesions (HEL) and human uterine fibromas (HUF) are not well characterized. This study aimed to characterize …

Published: Dec. 29, 2025, midnight
THBS1 identificated as an endometriosis biomarker through evidence from single-cell and bulk transcriptomic profiling.

Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and …

Published: Nov. 21, 2025, midnight
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