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AIF-1 Modulates Endometrial Stromal Cell Proliferation, Invasion, and Migration via Mitochondrial Function.

This study investigates the role of allograft inflammatory factor 1 (AIF-1) in regulating the proliferation, invasion, and migration of endometrial stromal cells (ESCs) in the context of endometriosis, focusing on …

Published: Sept. 19, 2025, midnight
The role of mitochondrial DNA copy number in female infertility: a bidirectional two-sample Mendelian randomization study.

Previous studies on the impact of mitochondrial DNA (mtDNA) copy number on female infertility were limited and inconsistent.

Published: Dec. 23, 2024, midnight
The mitochondrial DNA copy number and ovary-related reproductive disorders: A bidirectional two-sample Mendelian randomization study.

In the present study, a bidirectional two-sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA-CN) and ovary-related reproductive disorders (ORRDs), including ovarian …

Published: Nov. 30, 2024, midnight
Concurrent detection of the mitochondrial DNA copy number and the +35G/C polymorphism in the mitochondrial transcription factor A gene in endometriosis.

Endometriosis is a chronic gynecological inflammatory disease. The mitochondrial DNA copy number (mtDNA CN) and mitochondrial transcription factor A (TFAM) are known to contribute to human pathologies and cancer. Therefore, …

Published: Sept. 10, 2024, midnight
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