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Charting the nerve-immune axis in endometriosis.

Endometriosis is increasingly recognized as a systemic disorder involving complex interactions between nerves and immune cells, driving chronic pain and inflammation beyond the initial theories. Recent breakthroughs highlight aberrant sensory …

Published: March 26, 2026, midnight
Innervation of the Uterus: An Anatomical Study With Application to Better Understanding Pelvic Pain in Women.

Pelvic pain has a significant impact on quality of life, especially when associated with benign pelvic diseases, such as endometriosis or chronic conditions leading to persistent discomfort. A substantial proportion …

Published: Feb. 1, 2026, midnight
The Histamine-Associated Inflammatory Landscape of Endometriosis: Molecular Profiling of HDC, HRH1-HRH4, and Cytokines Across Lesion Subtypes.

Pain in endometriosis involves not only nociceptive but also neuropathic and neurogenic components, reflecting its complex nature. Histamine, a biogenic amine, has emerged as a critical mediator connecting inflammation and …

Published: Dec. 24, 2025, midnight
Neuroinflammation is responsible for pain in endometriosis - targeting the JAK-STAT pathway and mast cell activation.

Chronic pain is a defining feature of endometriosis and contributes significantly to the diminished quality of life observed in affected individuals. Despite advances in understanding disease pathology, current therapeutic strategies …

Published: Aug. 29, 2025, midnight
Endometrial Nerve Fiber Density and Pain in Women With Endometriosis - Physician's Weekly

Endometrial Nerve Fiber Density and Pain in Women With Endometriosis Physician's Weekly

Published: April 2, 2025, 10:29 a.m.
Influence of endometrial nerve fibers and hormones on pain in women with endometriosis.

The mechanisms behind endometriosis-related pain are not yet fully understood. To determine if there is a difference in the density of endometrial nerve fibers between women with endometriosis and healthy …

Published: April 1, 2025, midnight
Serum neurofilament light chain levels in patients with small-fiber neuropathy.

Serum neurofilament light chain (sNfL) levels are an increasingly employed tool for the assessment of active axonal injury in a variety of neurological disorders including polyneuropathy. Injury to the small …

Published: Feb. 21, 2025, 12:04 a.m.
Serum neurofilament light chain levels in patients with small-fiber neuropathy.

Serum neurofilament light chain (sNfL) levels are an increasingly employed tool for the assessment of active axonal injury in a variety of neurological disorders including polyneuropathy. Injury to the small …

Published: Dec. 27, 2024, midnight
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