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Glycolytic reprogramming in endometriosis: molecular mechanisms, immune modulation, and non-hormonal therapeutic opportunities.

Endometriosis is a chronic gynecological disorder characterized by ectopic tissue growth and significant morbidity, yet current hormonal and surgical treatments often fail to prevent recurrence or entail severe side effects. …

Published: May 25, 2026, midnight
Menstrual Effluent in the Pathogenesis and Diagnosis of Endometriosis-A Systematic Review.

Background: The individual and social burden of endometriosis is high, and the diagnosis is usually delayed by 7-10 years. Menstrual effluent (ME) represents an accessible and uniquely informative biofluid. This …

Published: Feb. 26, 2026, midnight
Serum metabolic fingerprinting for diagnosis and therapeutic applications of ovarian endometriosis.

Ovarian endometriosis (OvE) is a gynecological disorder with endometrial tissue in the ovaries, for which effective non-invasive diagnosis and curative treatments are currently lacking. Serum samples were collected from both …

Published: Feb. 2, 2026, midnight
Identification of a circulating immunological signature as a liquid biopsy approach for the diagnosis of endometriosis.

Endometriosis is a chronic inflammatory disease characterized by ectopic endometrial tissue growth, causing pain and infertility. Diagnosis is often delayed due to reliance on imaging and invasive methods, highlighting the …

Published: Jan. 23, 2026, midnight
Urinary microRNAs for the non-invasive diagnosis of endometriosis identified by next-generation sequencing and machine learning.

Endometriosis is a chronic gynecological disease associated with pain, infertility, and delayed diagnosis. Non-invasive biomarkers are urgently needed to facilitate earlier detection and reduce the reliance on diagnostic laparoscopy. MicroRNAs …

Published: Jan. 7, 2026, midnight
Ultrasound as a non-invasive diagnostic tool to detect deep endometriosis using the International Deep Endometriosis Analysis terminology.

To evaluate the performance of transvaginal ultrasound (TVS) using the International Deep Endometriosis Analysis (IDEA) terminology in the detection of deep endometriosis (DE).

Published: Dec. 29, 2025, midnight
Non-Invasive Diagnosis of Endometriosis by Questionnaires in Patients Using Contraception.

Background/Objectives: The assessment of endometriosis (EMS)-associated pain is important, but only very few studies address the potential use of questionnaires for non-invasive prediction of the disease. Methods: In a prospective …

Published: Dec. 20, 2025, midnight
Development of an AI-based magnetic resonance imaging reading support program (AMP) for deep endometriosis diagnosis.

Diagnosis of endometriosis faces significant challenges including diagnostic delay and reliance on invasive procedures. Deep endometriosis (DE) poses additional difficulties in non-invasive diagnosis due to its subtle and complex imaging …

Published: Dec. 8, 2025, midnight
Urine and Serum miRNA Signatures for the Non-Invasive Diagnosis of Adenomyosis: A Machine Learning-Based Pilot Study.

Background: Adenomyosis remains difficult to diagnose non-invasively due to clinical overlap with endometriosis and the limited specificity of imaging techniques. This pilot study evaluated whether serum- and urine-derived microRNA (miRNA) …

Published: Nov. 26, 2025, midnight
Serum Galectin-1 as a Diagnostic Biomarker in Endometriosis: A Prospective Longitudinal Study.

Endometriosis is a chronic condition characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects ~10% of reproductive-aged individuals and is associated with dysmenorrhea and infertility. Although …

Published: Oct. 25, 2025, midnight
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