Precision medicine may be on the way for patients with endometriosis Medical Xpress
Precision medicine applications depend on elucidating the underlying molecular mechanisms of disease. However, many disorders, such as endometriosis, remain poorly characterised genetically due to data scarcity, positive-unlabelled (PU) imbalance, and …
Precision Medicine May Be on the Way for Patients with Endometriosis Yale School of Medicine
Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial-like tissue outside the uterine cavity. It affects approximately 10-15% of women of reproductive age globally and is characterized …
Endometriosis (EMs) is an estrogen-dependent, chronic inflammatory disorder characterized by immune microenvironment dysregulation, a critical factor in its pathogenesis. Despite existing therapies, limitations persist, highlighting the urgent need for innovative …
Gynecological diseases-encompassing polycystic ovary syndrome, endometriosis, infertility, and malignancies-represent a significant global health burden affecting women's quality of life, reproductive capacity, and long-term health outcomes. While traditional diagnostics rely on …
Endometriosis is a complex condition affecting 10% of reproductive-age women worldwide, yet its study has long been hindered by the shortcomings of traditional research models. This review aims to propose …
Endometriosis is traditionally conceptualized as a pelvic lesion-centered disease; however, mounting evidence indicates it is a chronic, systemic, and multifactorial inflammatory disorder. This review examines the molecular dialog between ectopic …
Female infertility is a multifactorial condition with complex biological and clinical underpinnings. Biologically, female-related infertility may stem from disruptions in the hypothalamic-pituitary-ovarian (HPO) axis, impaired folliculogenesis, oocyte maturation defects, uterine …
Background/Objectives: Endometriosis is a chronic, inflammatory, estrogen-dependent disease that has historically been underdiagnosed, especially in patients with unexplained infertility. On average, diagnosis is delayed by 11 years, underscoring the need …