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Harnessing mangroves for epigenetic therapies.

Mangroves are valuable reservoirs of diverse phytochemicals with significant therapeutic potential. Beyond their ecological roles, these bioactive compounds can influence epigenetic mechanisms, heritable changes in gene expression without alterations in …

Published: March 30, 2026, midnight
Global epidemiology of ovarian cancer: patterns, trends, and risk factors.

Ovarian cancer was the eighth most frequently diagnosed cancer among women in 2022. The global age-standardized incidence rate of ovarian cancer decreased from 7.22/100,000 to 6.71/100,000 from 1990 to 2021. …

Published: March 24, 2026, midnight
Medical Treatment for Endometriosis: One Size Does Not Fit All.

Endometriosis is associated with nociceptive pain, as well as peripheral and central sensitization. Evidence-based treatment suggestions for controlling endometriosis should be based on the convergence of the best scientific evidence, …

Published: March 21, 2026, midnight
Risk factors for acute pain after transvaginal ultrasound-guided oocyte retrieval: a retrospective study (2023-2024).

Transvaginal ultrasound-guided oocyte retrieval is required for assisted reproductive technology. This is a short and minimally invasive, but painful procedure. There are no clinical guidelines on optimal pain management. We …

Published: March 15, 2026, midnight
HIGH VERSUS STANDARD DOSE FOLIC ACID SUPPLEMENTATION FOR MISCARRIAGE PREVENTION: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.

To assess whether high-dose folic acid supplementation (4-5 mg/day), initiated before conception, reduces the risk of miscarriage and improves pregnancy rates compared to standard-dose supplementation (0.4 mg/day).

Published: March 11, 2026, midnight
From lipid profiles to disease onset: Triglycerides as predictive biomarkers in endometriosis.

Dyslipidaemia is related to endometriosis, but it is not known which lipid component is most relevant, and whether the observed correlation reflects the causal relationship. The relationship between triglycerides (TG) …

Published: March 7, 2026, midnight
Mechanism study of phthalate exposure promoting endometriosis: Based on the ferroptosis perspective.

Phthalates (PAEs), typical endocrine-disrupting chemicals (EDCs) that accumulate in the human body to induce reproductive toxicity, have epidemiological links to endometriosis (EM), but the underlying micro-mechanisms remain unclear. Ferroptosis is …

Published: March 2, 2026, midnight
Dietary Fiber in Endometriosis: Mechanisms, Evidence, and Potential Clinical Benefits-Up-to-Date Review.

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder. It is associated with hormonal dysregulation, pelvic pain, and a reduced quality of life. Dietary factors may influence disease development and symptom …

Published: Feb. 21, 2026, midnight
Influence of Oxidative Stress-Mediated Inflammation on the Pathogenesis of Reproductive Disorders: Exploring the Benefits of Carnosine for Prevention and Treatment of Endometriosis.

Endometriosis is a chronic pathological condition characterized by the growth of endometrial-like tissue outside the uterine cavity and is frequently associated with severe pain, persistent inflammation, and fibrosis within the …

Published: Jan. 30, 2026, midnight
Effects of endocrine disrupting chemicals and plasma metabolome on female reproductive diseases: A multidimensional Mendelian randomization study.

Endocrine disrupting chemicals (EDCs) have been associated with disorders affecting female reproductive health, although the precise causal connections and underlying pathways between these substances and such disorders remain incompletely elucidated. …

Published: Jan. 22, 2026, midnight
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