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Dienogest-associated capillaroscopic abnormalities: a case report and narrative review of progestin microvascular effects.

Progestins are widely used for endometriosis with proven efficacy and favorable safety. Their microvascular effects, however, are not fully understood. We report a 35-year-old woman who developed recurrent hand erythema …

Published: May 25, 2026, midnight
Adenomyosis Pathophysiology, Diagnostic Advances, and Therapeutic Options.

Adenomyosis is a heterogeneous, nonmalignant uterine disorder characterized by ectopic endometrium within the myometrium, leading to abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, and subfertility. Once considered a disease of …

Published: April 2, 2026, midnight
Thoracic endometriosis in an inoperable patient.

In this case report, we present a case of a woman in her 30s who was diagnosed with thoracic endometriosis presenting as a large pulmonary mass. Hormonal treatment progestin (synthetic …

Published: April 2, 2026, midnight
Menopausal hormone use after hysterectomy in endometriosis: a Finnish register-based study.

This study aimed to examine the frequency and type of menopausal hormone therapy (MHT) use after hysterectomy among women with surgically diagnosed endometriosis.

Published: April 1, 2026, midnight
Clinical and endocrine effects of pharmacological therapy in endometriosis: a systematic review and meta-analysis.

Endometriosis, PCOS, adenomyosis, and dysmenorrhea are major illnesses. Hormonal as well as non-hormonal treatments were evaluated for COCs, progestins, GnRH analogues, LNG-IUS, relugolix, and adjunctive therapies. These treatments resulted in …

Published: April 1, 2026, midnight
Epigenetic biomarkers of progestin-resistance in endometriosis.

Published: March 18, 2026, midnight
Repeatedly occurring retrograde menstruation intensifies central sensitization driven by neuroinflammation in endometriosis models.

This study investigated how chronic pelvic pain (CPP) develops using rhesus macaques with naturally occurring endometriosis and a multiple-lesion induction mouse model (MIM), as repeated retrograde menstruation is considered an …

Published: March 17, 2026, midnight
Impact of combined oral contraceptives and progestin-only pills on psychological and sexual well-being of women with endometriosis: A systematic review.

Women with endometriosis frequently experience psychological and sexual concerns. Combined oral contraceptives (COCs) and progestin-only pills (POPs) represent first-line treatments for the disease, yet their potential negative impact on mood …

Published: March 12, 2026, midnight
Changing the paradigm of endometriosis - from diagnosis to integrated long-term management: a joint society opinion paper.

Endometriosis is a chronic, systemic, oestrogen-dependent disease with major impacts on pain, fertility and quality of life. This Society of Endometriosis and Uterine Disorders and American Institute for Minimally Invasive …

Published: Feb. 24, 2026, midnight
Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

Endometriosis is a complex, estrogen-dependent disease with limited effective treatments that often focus on symptom management rather than addressing the underlying pathology. Current therapies, such as progestins and GnRH agonists, …

Published: Feb. 13, 2026, midnight
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