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Descriptive overview of gene variants potentially affecting female infertility treatments: A systematic review.

Pharmacogenetics is an emerging discipline that explores how genetic variants affect drug response, potentially leading to side effects or treatment failure. Although widely applied in other medical specialties, its use …

Published: Jan. 6, 2026, midnight
Lack of Scientific Evidence for the Use of Gestrinone in the Treatment of Lipedema: A Systematic Review.

Lipedema is a chronic, progressive disorder marked by the abnormal accumulation of subcutaneous adipose tissue, predominantly in the lower body and almost exclusively affecting women. In recent years, the off-label …

Published: Nov. 19, 2025, midnight
Ethanol sclerotherapy for management of endometriomas: an overview of systematic reviews.

Evidence suggests that endometrioma cystectomy can significantly reduce ovarian reserve. Ethanol sclerotherapy is a promising, minimally invasive alternative. This overview aims to critically evaluate systematic reviews that addressed the safety …

Published: Nov. 18, 2025, midnight
Digital Health Technologies in the Treatment of Chronic Pelvic Pain Syndromes: A Systematic Review of Randomized Clinical Trials.

Objective: To comprehensively examine the qualitative results of current studies reporting the efficacy of digital health (DH) technologies in the treatment of chronic pelvic pain syndromes (CPPS) and to describe …

Published: Oct. 22, 2025, midnight
The Diagnostic Performance of Transvaginal Ultrasound for Posterior Compartment Endometriosis Compared to Laparoscopic and Histopathological Findings: A Systematic Review.

Background: Deep infiltrating endometriosis (DIE) frequently affects the posterior pelvic compartment, where accurate non-invasive imaging is essential for diagnosis and surgical planning. Aim: This systematic review evaluates the diagnostic performance …

Published: Oct. 10, 2025, midnight
Efficacy of Elagolix and Relugolix for the Treatment of Pelvic Pain in Patients With Endometriosis: A Systematic Review.

Endometriosis is a chronic gynecological condition commonly associated with pelvic pain, dysmenorrhea, dyspareunia, and infertility. Owing to the limitations and adverse effects of traditional hormonal therapies, this study aimed to …

Published: Sept. 12, 2025, midnight
New Perspectives on the Use of Resveratrol in the Treatment of Metabolic and Estrogen-Dependent Conditions Through Hormonal Modulation and Anti-Inflammatory Effects.

Estrogen-dependent conditions, such as endometriosis, adenomyosis, lipedema, polycystic ovary syndrome, and breast cancer, are intimately involved with hormonal changes related to estrogen and their receptors. These conditions can be expressed …

Published: Aug. 27, 2025, midnight
Eligibility criteria for the use menopausal hormone therapy (MHT) in women with medical conditions (II): Endometriosis, neurological and autoimmune diseases.

This project developed eligibility criteria for menopausal hormone therapy in patients with medical conditions beyond those published in a previous report. A new consortium of scientific societies coordinated by the …

Published: Jan. 30, 2025, midnight
Reproductive outcomes in infertile women with endometriosis undergoing ART.

Background Endometriosis-related infertility and its treatment with assisted reproductive technologies (ART) have been broadly researched. Yet, underlying mechanisms of infertility, particularly in the absence of tubal dysfunction, remain unclear. While …

Published: Jan. 25, 2025, midnight
Improving Replication in Endometrial Omics: Understanding the Influence of the Menstrual Cycle.

The dynamic nature of human endometrial tissue presents unique challenges in analysis. Despite extensive research into endometrial disorders such as endometriosis and infertility, recent systematic reviews have highlighted concerning issues …

Published: Jan. 20, 2025, midnight
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