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Beyond Antioxidant Activity, Towards Redox Modulation: N-Acetylcysteine (NAC) in Endometriosis and Uterine Leiomyomas.

Endometriosis and uterine leiomyomas are common chronic gynecologic diseases associated with immune dysregulation, inflammation and aberrant cellular proliferation, processes that contribute to increased oxidative stress. Current management relies largely on …

Published: July 27, 2026, midnight
Severe anemia and red cell product ordering burden among women hospitalized with benign uterine disorders: a retrospective cohort study using MIMIC-IV.

Benign uterine disorders, including uterine leiomyomas and uterine endometriosis/adenomyosis-related conditions, are common causes of gynecologic morbidity and represent an important women's health issue. Although these conditions are generally non-malignant, a …

Published: July 20, 2026, midnight
Benign Metastasizing Leiomyoma With Myomatous Erythrocytosis Syndrome: First Reported Coexistence as a Unified Hormonal Syndrome.

Benign metastasizing leiomyoma (BML) is a rare condition characterized by histologically benign smooth muscle tumours arising at extrauterine sites, most commonly the lungs, in women with a history of uterine …

Published: July 15, 2026, midnight
A Rare Coexistence: Uterine Leiomyoma Arising in a Mature Cystic Teratoma and a Pedunculated Endometriotic Cyst Mimicking Leiomyoma-Two Case Reports.

Uterine leiomyomas are common benign tumors, but their clinical presentation can be misleading. We report two unusual cases of pedunculated uterine masses presenting with heavy vaginal bleeding. In the first …

Published: June 21, 2026, midnight
A logistic regression model for predicting postoperative recurrence of cellular uterine leiomyoma.

The risk factors for the postoperative recurrence of cellular uterine leiomyoma (CUL) remain unclear.This study aimed to identify independent risk factors for recurrence and to develop a predictive model based …

Published: June 17, 2026, midnight
Preclinical models of female pelvic pain disorders.

Pain is influenced by a complex interplay of biological, psychological, and social factors. Sex has emerged as a key determinant of vulnerability to chronic pain and a major risk factor …

Published: May 20, 2026, midnight
Pathogenesis of Adenomyosis: An Integrated Review of Cellular Origins, Molecular Mechanisms, and Intersecting Diseases.

Adenomyosis is a prevalent disorder of the archimetra, historically conflated with endometriosis but possessing a unique pathobiological trajectory. This review synthesises current molecular evidence to propose a unified mechanistic framework …

Published: April 14, 2026, midnight
Genetically-predicted placental gene expression links to uterine fibroids and endometriosis.

Mother-to-child disease transmission begins in utero, with the placenta playing a critical role in pregnancy and offspring health. Uterine leiomyomata (fibroids, UFs) and endometriosis (ENDO) are common gynecologic diseases that …

Published: April 1, 2026, midnight
Beyond VEGF and TGF-β: A Comprehensive Review of Growth Factor Pathways in the Pathophysiology of Uterine Leiomyomas.

Uterine leiomyomas or fibroids, are non-cancerous smooth muscle proliferations of the uterus, occurring mostly in women of reproductive age. Their pathogenesis involves complex growth factor interactions that regulate cellular proliferation, …

Published: Jan. 1, 2026, midnight
Severe Anemia (1.4 g/dL) Due to Uterine Fibroid Bleeding With Reversible Myocardial Dysfunction: A Case Report.

Abnormal uterine bleeding (AUB), particularly when associated with uterine leiomyomas, is a frequent cause of iron deficiency anemia among women of reproductive age. While commonly manageable, in rare instances, AUB …

Published: Dec. 31, 2025, midnight
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