Endocrine disruptors (EDs) are a heterogeneous group of natural or synthetic chemicals capable of interfering with hormonal regulation. Widely present in plastics, cosmetics, pesticides, food packaging, and household products, they …
How do cumulative live birth rates (CLBRs) in women with endometriosis compare to those with other infertility diagnoses undergoing ART?
To investigate the feasibility of magnetic resonance imaging (MRI) in detecting and classifying adhesions between pelvic organs caused by endometriosis, comparing MRI findings to those obtained by laparoscopy.
The endometrium is a highly dynamic tissue central to female reproductive function, undergoing nearly 500 cycles of proliferation, differentiation, shedding, and regeneration throughout a woman's reproductive life. This remarkable regenerative …
Many experimental and clinical studies published so far demonstrate that melatonin-produced mainly by the pineal gland located deep in the middle of the brain, between the two cerebral hemispheres, and …
Endometriosis is a chronic inflammatory condition often associated with infertility. The role of granzymes as cytotoxic proteases and immune regulators in endometriosis remains poorly understood. This study evaluated serum and …
Ectopic pregnancy (EP) and tubal endometriosis (TEM) directly affect the fallopian tube structure and function, while ovarian cysts (OC) and uterine fibroids (UF) may indirectly influence tubal physiology. These conditions …
The female reproductive system (FRS) exhibits unique immunological characteristics, balancing defense against pathogens with tolerance to sperm and semi-allogeneic embryos. Key players include decidual natural killer (dNK) cells, immune checkpoint …
Endometriosis is a prevalent, estrogen-dependent, inflammatory disease that impairs fertility via hormonal dysregulation, immune dysfunction, oxidative stress/ferroptosis, genetic and epigenetic alterations, and microbiome imbalance. We summarize multi-omics insights and clinical …
Endometriosis represents a predominant gynecological disease that globally impacts 10% of women in their reproductive years, often leading to pelvic pain, infertility, and other complications.