Latest Articles

The effect of tinzaparin sodium and leuprolide acetate in an experimental mouse model of endometriosis: The rol of the WNT/beta-catenin pathway.

Endometriosis is a benign condition driven by estrogen and inflammation in which endometrial-like tissue develops in ectopic locations. We aimed to determine whether non-steroidal agents acting on the WNT/beta-catenin signaling …

Repurposing ramipril to mitigate EMT-like transition in endometriosis by PI3K/AKT/S6K1 signalling pathway: a study in endometriosis induced rats.

Endometriosis, an atypical benign disorder, may disrupt epithelial-mesenchymal transition (EMT) due to a dysregulated balance between matrix metalloproteinases (MMPs) and their inhibitors. Ramipril, an angiotensin converting enzyme (ACE) inhibitor, is …

HAGLR promotes endometriosis progression via the miR-185-5p/VEGFA axis and serves as a potential diagnostic biomarker.

Identification of a circulating immunological signature as a liquid biopsy approach for the diagnosis of endometriosis.

Endometriosis is a chronic inflammatory disease characterized by ectopic endometrial tissue growth, causing pain and infertility. Diagnosis is often delayed due to reliance on imaging and invasive methods, highlighting the …

Uterine Vulnerability: A Lived Experience Response to Endometriosis.

In this article, I examine the uterus as an object in relation to endometriosis and the epistemological struggle of sufferers to have their pain taken seriously. Defined by endometrial-like tissue …

Thoracic endometriosis syndrome posing diagnostic and therapeutic challenges in a low-resource setting: a case report.

Thoracic endometriosis syndrome is an uncommon condition defined by the existence of functional endometrial tissue outside of the uterine cavity, specifically in the pleura, lung parenchyma, or airways. We present …

The Reproductive Tract Microbiome and Female Fertility: Dysbiosis, Disease Links, and Emerging Therapeutic Strategies.

The reproductive tract microbiome plays a pivotal role in female fertility, with Lactobacillus-dominated communities maintaining a protective, low-pH environment. Dysbiosis-characterized by a reduction in Lactobacillus species and overgrowth of anaerobes-is …

Noninvasive Imaging Diagnostics for Endometriosis.

Endometriosis is a prevalent gynecological condition affecting approximately 10% of women of reproductive age and up to 50% of those with infertility. It is characterized by the presence of endometrial-like …

Targeting endometrial stem cell in endometriosis treatment, a scoping review.

Endometriosis is characterized by the ectopic implantation of endometrial tissue affecting reproductive-aged women. Available therapies have still unmet needs namely due to recurrence rates and systemic side effects. Emerging evidence …

Hormonal treatment in endometriosis fails to prevent IL-6 increase and endometrium fibrosis but regulates levels of CYP17A, VEGF, and NFkB.

Endometriosis is a gynecological inflammatory disease characterized by the presence of ectopic endometrial-like tissue. This study aims to elucidate the effect of hormonal treatment in human endometriosis inflammation, angiogenesis and …