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Antagonizing the corticotropin-releasing hormone receptor 1 with an orally bioavailable drug reduces endometriosis pain and associated adhesions†.

Estrogen stimulates corticotropin-releasing hormone (CRH) expression in endometrial tissue, and CRH signaling contributes to inflammation and pain, suggesting a mechanistic role in endometriosis pathophysiology. We previously identified elevated CRH receptor-1 …

Published: May 22, 2026, midnight
Small bowel herniation through a caesarean section wound presenting as cellulitis: A case report.

Small bowel herniation through a Caesarean section wound is exceedingly rare and may present with erythema and induration clinically indistinguishable from superficial wound infection, risking dangerous diagnostic delay. A case …

Published: May 22, 2026, midnight
From gut-reproductive microbiota to ferroptosis: a comprehensive insight into the molecular-pathogenicity of endometriosis.

Endometriosis (EMS) is a highly heterogeneous chronic gynecological disease characterized by pain, infertility, and relapse, with its etiology and pathogenesis not yet fully elucidated. Traditional theories, including "retrograde menstruation," "implantation …

Published: May 22, 2026, midnight
Lead concentration in follicular fluid of infertile patients with and without endometriosis: a propensity score matching exploratory study.

This preliminary study sought to provide initial insights into lead concentrations within the follicular fluid of infertile patients with and without endometriosis, tentatively observing any potential links between lead presence …

Published: May 22, 2026, midnight
Bioinformatics and machine learning-driven discovery of candidate tissue diagnostic markers for endometriosis with experimental verification.

Endometriosis is a complex gynecological disorder lacking reliable biomarkers. This study aimed to identify core diagnostic genes through integrated computational approaches. Multiple endometriosis transcriptomic datasets were analyzed.

Published: May 22, 2026, midnight
Extracellular Vesicles in Endometriosis: A Comprehensive Review of Biological Insights and Methodological Challenges.

Endometriosis is a complex disorder associated with dysregulated immune, hormonal, and microenvironmental signaling. Extracellular vesicles (EVs) are important mediators of intercellular communication and may contribute to disease pathogenesis, biomarker discovery, …

Published: May 22, 2026, midnight
Correlations Between Ultrasound Features and Histological Findings in Adenomyosis: A Single-Center Retrospective Study.

Adenomyosis is a benign gynecologic condition characterized by ectopic endometrial glands and stroma present within the myometrium. Background/Objectives: The gold standard in diagnosis is the histology of hysterectomy specimens. Due …

Published: May 22, 2026, midnight
Does endometrioma diameter impact serum anti-Müllerian hormone levels? A systematic review and meta-analysis.

Is endometrioma diameter associated with ovarian reserve, as reflected by serum anti-Müllerian hormone (AMH) levels, in women of reproductive age with no history of ovarian surgery?

Published: May 22, 2026, midnight
ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol.

Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptions hinder effective management, particularly …

Published: May 21, 2026, midnight
Developmental Versus Chromosomal Competence in Endometriosis: A Stepwise IVF Outcome Analysis.

Background and Objectives: Endometriosis is a multifactorial gynecological condition associated with impaired fertility; however, its impact on embryo competence remains incompletely understood. This study aimed to evaluate embryo competence through …

Published: May 21, 2026, midnight
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