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The Role of Exosomal miRNAs in Female Infertility: Therapeutic Potential and Mechanisms of Action.

Reproductive disorders, including preeclampsia (PE), endometriosis, premature ovarian failure (POF), and polycystic ovary syndrome (PCOS), present substantial challenges to women's reproductive health. Exosomes (EXOs) are cell-derived vesicles containing molecules that …

Published: March 24, 2025, midnight
Therapeutic Effects and Mechanisms of Alcohol Extracts from Polygala fallax Hemsl on Endometriosis in Rats.

Endometriosis is a chronic estrogen-dependent inflammatory disease that significantly affects women's health. Polygala fallax Hemsl. (PFH), a traditional Zhuang medicine, has been frequently used for gynecological disorders. This study investigated …

Published: March 14, 2025, midnight
Impact of miR-214-5p and miR-21-5p From Hypoxic Endometrial Exosomes on Human Umbilical Cord Mesenchymal Stem Cell Function | Newswise - Newswise

Impact of miR-214-5p and miR-21-5p From Hypoxic Endometrial Exosomes on Human Umbilical Cord Mesenchymal Stem Cell Function | Newswise Newswise

Published: Feb. 26, 2025, 5 p.m.
Engineered Exosomes Restore miR-508-5p Expression in Uterine Corpus Endometrial Carcinoma and Reduce Tumor Progression and Metastasis by Targeting DLL3 - Frontiers

Engineered Exosomes Restore miR-508-5p Expression in Uterine Corpus Endometrial Carcinoma and Reduce Tumor Progression and Metastasis by Targeting DLL3 Frontiers

Published: Feb. 3, 2025, 2:27 p.m.
Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression.

Endometriosis development is associated with peritoneal immune microenvironment abnormality; however, the specific mechanism is uncertain. We aimed to investigate the effects and underlying mechanisms of uterine cavity-derived exosomes on macrophage …

Published: Jan. 9, 2025, midnight
Transcriptomics of tissue exosomes to investigate miR-195-5p’s amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study - Journal of Translational Medicine

Transcriptomics of tissue exosomes to investigate miR-195-5p’s amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study Journal of Translational Medicine

Published: Nov. 21, 2024, 10:05 a.m.
Effects of Exosomes from Menstrual Blood-derived Stem Cells and Ginger on Endometriotic Stem Cells.

Menstrual blood-derived stem cells from endometriosis patients (E-MenSCs) have different gene expression patterns than those from healthy nonendometriotic females (NE-MenSCs). Exosomes extracted from mesenchymal stem cells and plants are considered …

Published: Nov. 20, 2024, midnight
The Application of Nano Drug Delivery Systems in Female Upper Genital Tract Disorders.

The prevalence of female reproductive system disorders is increasing, especially among women of reproductive age, significantly impacting their quality of life and overall health. Managing these diseases effectively is challenging …

Published: Nov. 19, 2024, midnight
Exosomal miR-202 derived from leukorrhea as a potential biomarker for endometriosis.

Endometriosis (EMS) is a chronic gynecological disorder with an urgent need of a reliable non-invasive diagnostic strategy. Recently, there has been increasing interest in using the contents of exosomes, especially …

Published: Oct. 14, 2024, 1:25 p.m.
(PDF) A comprehensive overview of exosome lncRNAs: emerging biomarkers and potential therapeutics in endometriosis - ResearchGate

(PDF) A comprehensive overview of exosome lncRNAs: emerging biomarkers and potential therapeutics in endometriosis ResearchGate

Published: July 6, 2024, 7 a.m.
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