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Microvascular hypoxia and inflammation in chronic pain syndromes.

In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …

Published: Dec. 8, 2025, midnight
Surgical Complexity, Disease Severity, and Direct Healthcare Costs of Endometriosis in the Brazilian Public Health System: A Cross-Sectional Analysis.

The objective was to evaluate the clinical and demographic characteristics of patients undergoing endometriosis surgery in the public healthcare system, estimate the direct costs related to low- and high-complexity procedures, …

Published: Dec. 8, 2025, midnight
Microbiome analysis of the cystic fluid in ovarian endometrioma: new avenues for the prevention, diagnosis, and treatment of the disease.

This study aimed to investigate the microbiome profile in the cystic fluid of ovarian endometrioma and explore its association with the microbial communities present in the lower and upper reproductive …

Published: Dec. 7, 2025, midnight
From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers.

Endometriosis, a chronic estrogen-dependent disease, is associated with a risk of developing gynecological cancers. The mechanisms of this association remain unclear, but emerging evidence implicates key signaling pathways, including PI3K/AKT/mTOR …

Published: Dec. 7, 2025, midnight
Impact of Physical Activity on Ovarian Response: A Prospective Study Among In Vitro Fertilization Patients.

Introduction Scientific evidence has shown that regular physical activity (PA) is beneficial to health. However, no consensus has been reached on the association between PA and the success rates of …

Published: Dec. 7, 2025, midnight
The "double-edged sword" effect of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of endometriosis (EMS).

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate pain associated with endometriosis (EMS), yet the impact of their long-term use on disease progression remains unclear. This study investigates the …

Published: Dec. 6, 2025, midnight
Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review).

Endometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly …

Published: Dec. 5, 2025, midnight
Sun's Bushen Huayu Formula Restores Fertility in Endometriosis by Modulating Th1 and Th2 Cytokine Balance in Clinical and Animal Models.

Endometriosis (EMs) is a common gynecological disorder frequently associated with infertility, yet the underlying immune mechanisms remain poorly understood. Sun's Bushen Huayu Formula (BSHYF) has been clinically applied to improve …

Published: Dec. 5, 2025, midnight
RETRACTED ARTICLE: Effects of Kuntai capsule on breast pain and vaginal bleeding in postmenopausal women.

Description Following a complaint and technical (editorial) investigation, the authors were requested to provide essential documentation to verify the reliability, validity, and ethical compliance of the study published. Despite repeated …

Published: Dec. 4, 2025, midnight
Laparoscopic treatment of bilateral inguinal round ligament endometriosis.

To demonstrate the laparoscopic management of bilateral round ligament endometriosis SETTING: A tertiary referral center specializing in minimally invasive gynecologic surgery.

Published: Dec. 4, 2025, midnight
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