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BCL6 (B-cell lymphoma 6) expression in adenomyosis, leiomyomas and normal myometrium.

Adenomyosis and leiomyomas are common benign uterine disorders characterized by abnormal cellular proliferation. The BCL6 protein, a transcriptional repressor implicated in cell proliferation and oncogenesis, has been linked to the …

Published: Feb. 4, 2025, midnight
Equilibrium mechanical properties of the human uterus in tension and compression.

A successful pregnancy relies on the proper cellular, biochemical, and mechanical functions of the uterus. A comprehensive understanding of nonpregnant and pregnant uterine mechanical properties is key to understanding different …

Published: Jan. 29, 2025, midnight
Management of Common Benign Gynecologic Diseases in Postmenopausal Women.

This study investigated the impact of menopause on the progression and management of common benign gynecological conditions such as polycystic ovary syndrome, endometriosis, uterine fibroids, and adenomyosis. These conditions often …

Published: Jan. 22, 2025, midnight
Mapping Human Uterine Disorders Through Single-Cell Transcriptomics.

Disruptions in uterine tissue function contribute to disorders such as endometriosis, adenomyosis, endometrial cancer, and fibroids, which all significantly impact health and fertility. Advances in transcriptomics, particularly single-cell RNA sequencing, …

Published: Jan. 21, 2025, midnight
Validation of biomarkers and clinical scores for the detection of uterine leiomyosarcoma: a case-control study with an update of pLMS.

The diagnosis of rare uterine leiomyosarcoma (uLMS) remains a challenge given the high incidence rates of benign uterine tumors such as leiomyoma (LM). In the last decade, several clinical scores …

Published: Jan. 8, 2025, midnight
Trocar scar abdominal wall adenomyoma following laparoscopic hysterectomy: case report.

Abdominal wall endometriosis (AWE) within the scar of a trocar insertion is seldom reported as a complication of laparoscopy. We describe the case of a 46 year-old woman suffering from …

Published: Nov. 20, 2024, midnight
Elective uterine preservation: a novel concept to tackle reproductive ageing. Fertility preservation beyond ovaries.

With a growing number of women in developed countries having children later in life, it is time to rethink women's reproductive health. This trend of 'delayed parenthood' reflects a complex …

Published: Nov. 10, 2024, midnight
A Rare Case of Low-Grade Endometrial Stromal Sarcoma Invading an Old Leiomyoma - Cureus

A Rare Case of Low-Grade Endometrial Stromal Sarcoma Invading an Old Leiomyoma Cureus

Published: Nov. 9, 2024, 1:47 p.m.
Childhood adversity and risk of endometriosis, fibroids, and polycystic ovary syndrome: A systematic review.

While childhood adversity has been extensively studied in relation to various health outcomes, investigation of its association with gynecological conditions remains limited.

Published: Nov. 7, 2024, midnight
Adenomyosis-associated infertility: an update of the immunological perspective.

Adenomyosis is characterized by the invasion of endometrial glands and stroma into the myometrium. Its clinical manifestations often include dysmenorrhoea, excessive menstrual bleeding and infertility. Reduced pregnancy and live birth …

Published: Nov. 6, 2024, midnight
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