Mechanisms of Endometrioma-Mediated Ovarian Damage: Myths and Facts.
Ovarian endometriomas (OEMs), cystic formations within the ovaries, are a significant manifestation of endometriosis and present in 20-40% of affected women. Despite extensive research, the pathogenesis of endometriosis remains unclear, …
Utilising Human Myometrial and Uterine Fibroid Stem Cell-Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids.
Uterine fibroids (UFs) are the most common benign gynecologic tumours affecting women of reproductive age. This study aims to deepen the understanding of UFs complex aetiology through harnessing the power …
Targeting ferroptosis for the treatment of female reproductive system disorders.
Ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has emerged as a critical factor in female reproductive health and has been implicated in disorders such as …
Using electronic health record data to identify incident uterine fibroids and endometriosis within a large, urban academic medical center: a validation study.
Electronic health records (EHRs) present opportunities to study uterine fibroids uterine fibroids and endometriosis within diverse populations. When using EHR data, it is important to validate outcome classification via diagnosis …