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EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.

Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …

Published: Dec. 19, 2025, midnight
Molecular Regulation of FOXO1 and Its Pathophysiological Significance in Endometriosis: A Narrative Review.

Endometriosis is a chronic inflammatory disorder that affects approximately 10% of women of reproductive age and exhibits tumor-like characteristics such as invasion, recurrence, and hormone-dependent proliferation despite its benign nature. …

Published: Dec. 19, 2025, midnight
Could the estrobolome have a role in endometriosis pathogenesis and infertility? A systematic review.

Endometriosis is a chronic, estrogen-dependent condition affecting 10% of reproductive-aged women, often associated with infertility and chronic pelvic pain. Recent evidence suggests that gut microbiota dysbiosis and alterations in the …

Published: Dec. 18, 2025, midnight
Endometriosis as an immune-mediated disease: pathogenetic mechanisms and therapeutic strategies.

Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …

Published: Dec. 18, 2025, midnight
Pharmacophoric Investigation of a Natural Product-like Class of Aromatase Inhibitors Using Molecular Modeling.

Endometriosis is a condition affecting approximately 10% of reproductive-age women in which endometrial tissue is found in locations outside the uterus, often causing debilitating symptoms. Aromatase, an enzyme that also …

Published: Dec. 18, 2025, midnight
New Genetic Health & Wellness Reports and Features - 23andMe

New Genetic Health & Wellness Reports and Features 23andMe

Published: Dec. 17, 2025, 9:53 p.m.
FDA Approves Lerochol for Lowering LDL Cholesterol Levels and Grants Priority Review Voucher for Tecvayli - geneonline.com

FDA Approves Lerochol for Lowering LDL Cholesterol Levels and Grants Priority Review Voucher for Tecvayli geneonline.com

Published: Dec. 17, 2025, 8:34 p.m.
newsGP - Top 10 global health stories of 2025 - Royal Australian College of General Practitioners (RACGP)

newsGP - Top 10 global health stories of 2025 Royal Australian College of General Practitioners (RACGP)

Published: Dec. 17, 2025, 5:46 a.m.
APOL1-mediated kidney disease: a narrative review of the lessons learnt from the past 15 years.

Fifteen years have elapsed since the publication of the seminal work establishing the association between risk variants in the Apolipoprotein L1 (APOL1) gene and kidney disease in individuals of African …

Published: Dec. 17, 2025, midnight
Study Links Oleic Acid to Tumor Growth in Endometrial Cancer Through Polyamine Accumulation - geneonline.com

Study Links Oleic Acid to Tumor Growth in Endometrial Cancer Through Polyamine Accumulation geneonline.com

Published: Dec. 16, 2025, 10:36 p.m.
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