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Mesenchymal stem cells: opening a new chapter in the treatment of gynecological diseases.

In recent years, mesenchymal stem cells (MSCs) have garnered significant attention as promising therapeutic tools for various diseases. To date, over ten MSC-based therapies have been approved and marketed worldwide, …

Published: Sept. 26, 2025, midnight
Menopause as a Critical Turning Point in Lipedema: The Estrogen Receptor Imbalance, Intracrine Estrogen, and Adipose Tissue Dysfunction Model.

Lipedema is a chronic, estrogen-sensitive adipose tissue disorder characterized by disproportionate subcutaneous fat accumulation, fibrosis, inflammation, and resistance to fat mobilization. Despite its high prevalence, lipedema remains poorly understood and …

Published: July 23, 2025, midnight
PCDD/Fs in human tissues: A review of global biomonitoring data.

This review investigates the concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in internal human organs and tissues - excluding blood - with a particular focus on adipose tissue studies conducted …

Published: March 27, 2025, midnight
Cell Migration in Endometriosis Responds to Omentum-Derived Molecular Cues Similar to Ovarian Cancer.

Endometriosis is common and poses significant morbidity of lasting impact to young, pre-menopausal women, while ovarian cancer is a lethal gynecologic condition. Both conditions need better treatment. The human omentum …

Published: Feb. 20, 2025, midnight
Medical therapy to treat obesity and optimize fertility in women of reproductive age: a narrative review.

Overweight and obesity-chronic illnesses in which an increase in body fat promotes adipose tissue dysfunction and abnormal fat mass resulting in adverse metabolic, biomechanical, and psychosocial health consequences-negatively impact female …

Published: Jan. 6, 2025, midnight
A narrative review about the intricate crosstalk among endometrium, adipose tissue, and neurons in endometriosis. The multifaceted role of leptin.

Endometriosis is a highly prevalent gynecological disease characterized by the presence of endometrium-like tissue outside the uterus, whose etiopathology is far from being elucidated. The most frequent complains of patients …

Published: Dec. 10, 2024, midnight
Prolapsed Epiploica of Colon Presenting as a Vaginal Polyp After Robotic Hysterectomy: A Case Report and Review of the Literature.

BACKGROUND Hysterectomy is a gynecological procedure that can lead to complications arising from structural changes incurred during the surgical process. Vaginal nodules may appear at the vaginal cuff after hysterectomy, …

Published: Nov. 28, 2024, midnight
Relationship between Cardiometabolic index and endometriosis in a US nationally representative sample: results from NHANES 1999-2006.

Endometriosis is an estrogen-dependent gynecological endocrine condition and a systemic inflammatory disease associated to improper lipid metabolism and increased cardiovascular risk. The Cardiometabolic Index (CMI) is a novel indicator representing …

Published: Nov. 12, 2024, midnight
Evidence of Browning and Inflammation Features in Visceral Adipose Tissue of Women with Endometriosis.

Patients with endometriosis tend to have a low body mass index, suggesting an inverse relationship between body fat and risk of disease. This is supported by evidence that miRNAs differentially …

Published: Sept. 7, 2024, midnight
Ultrasound Imaging of Abdominal Wall Endometriosis: A Pictorial Review.

Endometriosis is a debilitating disease characterized by endometrial glands and stroma outside the endometrial cavity. Abdominal wall endometriosis (AWE) indicates the presence of ectopic endometrium between the peritoneum and the …

Published: March 29, 2021, midnight
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