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The uterine secretome initiates growth of gynecologic tissues in ectopic locations: re-evaluating the evidence.

The origin of ectopic gynecologic lesions has been debated since 1927, when Sampson first proposed retrograde menstruation as the underlying cause of endometriosis. Reproduction in mammals is an unusually permissive …

Published: March 10, 2026, midnight
Compound design of a patient-derived 3D cell culture system modelling early peritoneal endometriosis.

Peritoneal endometriosis causes pelvic pain and infertility, but the underlying mechanisms related to these symptoms are not fully understood. Endometriosis diagnosis is typically delayed; thus, patient samples are unsuitable to …

Published: Dec. 15, 2025, midnight
Matrix Tropism Influences Endometriotic Cell Attachment Patterns.

The initiation of endometriotic lesions is not well understood or characterized because endometriosis is typically diagnosed at an advanced stage. Endometriotic lesions are most often found on pelvic tissues and …

Published: June 23, 2025, midnight
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